Herceptin is approved for the treatment of
early-stage breast cancer that is Human
Epidermal growth factor
(HER2+) and has spread into the lymph nodes, or is HER2+
and has not spread into the lymph nodes. If it has not
spread into the lymph nodes, the cancer needs to be
estrogen receptor/progesterone receptor (ER/PR)-negative or
have one high risk feature.* Herceptin can be used in
several different ways:
Important Patient Safety Information
Possible Serious Side Effects With HERCEPTIN
Not all people have serious side effects, but side effects with
HERCEPTIN therapy are common.
Although some people may have a life-threatening side effect,
most do not. Your doctor will stop treatment if any serious side
HERCEPTIN is not for everyone. Be sure to contact your doctor if
you are experiencing any of the following:
These signs usually happen within 24 hours after receiving
Be sure to contact your doctor if you:
If you stop treatment with HERCEPTIN, you should keep using birth control for at least 7 months before trying to become pregnant. If you are exposed to HERCEPTIN during pregnancy or within 7 months of becoming pregnant, you are encouraged to enroll in the MotHER Pregnancy Registry by contacting 1-800-690-6720.
Other Important Information
Side Effects Seen Most Often With
Some patients receiving HERCEPTIN for breast cancer had the following
- Feeling sick to your stomach (nausea)
- Throwing up (vomiting)
- Infusion reactions
- Increased cough
- Feeling tired
- Shortness of breath
- Low white and red blood cell counts
- Muscle pain
You should contact your doctor immediately if you have any of the side effects listed above.
You are encouraged to report side effects to Genentech and the FDA. You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at 1 (888) 835-2555.
Please see additional select Important Safety Information throughout, and the accompanying full Prescribing Information including Boxed WARNINGS.